BrainMVP: Multi-modal Vision Pre-training for Medical Image Analysis[CVPR2025 Highlight]

Shaohao Rui, Lingzhi Chen, Zhenyu Tang, Lilong Wang, Mianxin Liu, Shaoting Zhang, Xiaosong Wang

We introduce the first multi-modal vision pre-training method (BrainMVP) for missing modality medical data. We demonstrate the superior performance and the enhanced generalizability of our BrainMVP pre-trained models on ten public segmentation and classification benchmarks compared to state-of-the-art methods.

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InvCoSS: Inversion-driven Continual Self-supervised Learning in Medical Multi-modal Image Pre-training[CVPR 2026]

Zihao Luo*, Shaohao Rui*, Zhenyu Tang, Guotai Wang, Xiaosong Wang

* Equal contribution.

We propose InvCoSS, an inversion-driven continual self-supervised learning framework for medical multi-modal image pre-training. It synthesizes images by inverting prior-stage models—avoiding raw data replay—while mitigating catastrophic forgetting under privacy constraints. We introduce InvUNet for higher-fidelity inversion and repulsive representation learning to improve diversity; experiments on nine downstream tasks show performance comparable to or better than data-replay methods without storing past raw data.

Github

PackForcing: Short Video Training Suffices for Long Video Sampling and Long Context Inference[arXiv]

Xiaofeng Mao*, Shaohao Rui*, Kaining Ying, Bo Zheng, Chuanhao Li, Mingmin Chi, Kaipeng Zhang

* Equal contribution.

We present PackForcing, a framework for autoregressive video diffusion that manages generation history with a three-partition KV-cache: sink tokens for global semantics, highly compressed mid tokens (with dynamic top-k selection), and full-resolution recent tokens for local coherence, plus Temporal RoPE adjustment. It enables long coherent video generation with bounded memory—for example ~2-minute 832×480 video at 16 FPS on one H200 with ~4 GB KV cache and strong VBench temporal metrics—using only short-clip supervision.

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AdaThink-Med: Medical Adaptive Thinking with Uncertainty-Guided Length Calibration[ICML 2026]

Shaohao Rui, Kaitao Chen, Weijie Ma, Xiaosong Wang

We propose AdaThink-Med, an end-to-end framework that improves adaptive thinking in medical reasoning LLMs via uncertainty-guided length calibration—penalizing overly long chains on easy, solved cases while encouraging deeper reasoning on hard ones. On six medical QA benchmarks it cuts average output length by up to 6.4× with only minor accuracy loss and yields emergent “thinking” vs. “non-thinking” modes.

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CardioCoT: Hierarchical Reasoning for Multimodal Survival Analysis[ICASSP Oral]

Shaohao Rui, Haoyang Su, Jinyi Xiang, Lian-Ming Wu, and Xiaosong Wang

We propose CardioCoT, a hierarchical reasoning-enhanced survival analysis framework for MACE recurrence risk prediction in AMI patients, leveraging postoperative cardiac MRI and clinical notes. CardioCoT integrates evidence-augmented reasoning with imaging data, achieving superior predictive performance and interpretability to support precision clinical decision-making.

Github